Immunohistochemical and Molecular Features of Gastric Hyperplastic Polyps
نویسندگان
چکیده
منابع مشابه
Immunohistochemical and Molecular Features of Gastric Hyperplastic Polyps
Design: 15 large hyperplastic polyps (>1 cm), including 4 with dysplastic foci, 10 small hyperplastic polyps (≤1 cm), and 9 gastric adenomas were evaluated for immunohistochemical expression of MGMT, MLH-1, β-catenin, p27, p16, and p53. Polyps with dysplasia or abnormal β-catenin expression were assessed for APC and β-catenin (CTNNB1) mutations. Large hyperplastic polyps and adenomas were analy...
متن کاملMolecular characteristics of colorectal serrated polyps and hyperplastic polyps
The serrated neoplasia pathway of colorectal carcinogenesis is characterized by BRAF mutation and aberrant DNA methylation, which have not been reported on Korean patients. The aim of this study was to investigate BRAF mutation and DNA methylation in colorectal serrated polyps and the right colon.Between 2005 and 2013, 146 colon polyps (47 tubular adenomas [TAs], 53 traditional serrated adenoma...
متن کاملPathophysiological and clinical aspects of gastric hyperplastic polyps
Gastric polyps become a major clinical problem because of high prevalence and tendency to malignant transformation of some of them. The development of gastric hyperplastic polyps results from excessive proliferation of foveolar cells accompanied by their increased exfoliation, and they are macroscopically indistinguishable from other polyps with lower or higher malignant potential. Panendoscopy...
متن کاملMalignant transformation of hyperplastic gastric polyps: An immunohistochemical and pathological study of the changes of neoplastic phenotype
In spite of the evidence that the malignant transformation of gastric hyperplastic polyps (HPs) is a rare event, it must always be taken into account during diagnosis. The aim of the current study was to clarify the mechanism of the malignant transformation of gastric hyperplasia polyps, with focus on phenotypic expression, cell proliferation and p53 overexpression. Immunohistochemistry for muc...
متن کاملAre gastric hyperplastic polyps an additional manifestation in celiac disease?
Gastric polyps are frequently reported in patients undergoing upper endoscopic procedures. In this retrospective study, the association between hyperplastic polyps and celiac disease in Northern Sardinia was estimated.Age, gender, body mass index, and medications taken in the 2 preceding months, including proton-pump inhibitors (PPIs), H2 receptor blockers (anti-H2), Helicobacter pylori status,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advances in Cytology & Pathology
سال: 2017
ISSN: 2573-2862
DOI: 10.15406/acp.2017.02.00012